Ko bukti macam mana aku salah? Dengan tampal beberapa keratan di website yang bukan forte sains pun? Sedangkan ada lebih banyak website lagi yang mengatakan Sinovac guna live but weakened/inactivated virus.
Ni aku bagi journal. Sinovac guna Inactivated, bukan killed.
An overview of procurement, pricing, and uptake of COVID-19 vaccines in Pakistan
Killed and inactivated tak sama. Baca/tengok penerangan yang lebih saintific sikit seperti di Youtube atau di journal. Istilah yang digunakan adalah inactivated, bukan killed atau dead virus. Untuk orang yang bukan betul2 pure science, mungkin tak faham yang killed dan inactivated adalah tak sama.
Ni video, tunjuk mechanism Sinovac, guna live, weakened, inactivated virus. Ini memang channel yang memang focus kepada sains dan mechanism.
The virus was then grown in large numbers in Monkey Kidney cells before they were doused with a chemical called beta-propiolactone, the compound that disabled the coronavirus and stopped its replication.
Both are inactivated virusvaccines. This means they’re made from viral particles produced in a lab, which are then inactivated so they can’t infect you with COVID-19. Many other vaccines use similar platforms, including injectable polio, Hepatitis A and flu vaccines.
Post time 9-8-2021 11:34 AMFrom the mobile phone|Show all posts
snazzydaisy replied at 9-8-2021 06:41 AM
typical Herd Mentality...
bak kata pepatah - "It is easier to fool a person than to convince th ...
Yes la, kepandaian itu hanya di measured melalui college dan university dan pangkat saja lah, kalau anda tiada ni your words mean nothing, itu pasal lawyer, DR, accountant pun kena scam dengan Macau scam kannn.
Post time 9-8-2021 11:36 AMFrom the mobile phone|Show all posts
snazzydaisy replied at 9-8-2021 07:06 AM
They always (are required to) show us what they will do next but masih ramai yg pilih utk tutup se ...
Mereka boleh tutup mata and swept under the rug by tahun ni ler.....masuk tahun depan mereka dah tak mampu nak deny satu persatu apa yang kita bagi amaran bila satu persatu yang mereka kenali semua dah Innalilahhhh.......Allah lebih menyayangi.
Post time 9-8-2021 11:46 AMFrom the mobile phone|Show all posts
sarah82 replied at 8-8-2021 06:51 PM
Yg kena buat autopsy ke tak tu tak pasti.. Hepa filter tak ada lagi pasaran malaysia.. Yg LG pure ...
Sarah hang extra careful dengan pos package my mum kata 1 wherehouse di utara ada kena covid... Lazada or shopee aku tidak pasti.. Last month...
Philip blaise sudah check? paling sedap .. Compare to LG.... Tapi LG rasa lebih secure based dari design. actually sama saja....
Last aku beli sebelum balik.. banyak lagi... Ramai sekarang cari electric mask rupa nya....
Nampak perkataan kau tulis kat bawah ni , bukan stakat BBC dan NYtimes sebut dead /killed virus tapi jugak medical artikel kat bawah ni pungg terus terang sebut inactivated = dead virus.
So kau boleh dgn gahhh nya kata kau tau semua kat internet tarak sebut dead virus hanya BBC je bermakna aku dah buktikan kau tu gah je lebih yg kau tau semua kat internet tapi apa yg kau gah kan tuuu tak betul pungg kannn . Kerana bukan stakat BBC je sebut camtu .
Jgn sombong sgt dengan sains kau tu kerana apa yg kau ucap atau tuliskan dinilai berdasarkan betul atau tidak , bukan berdasarkan kau labelkannya sundrik sebagai sains lalu kau nak semua perlu telan bulat2 je .
There are several types of vaccines that can be used to fight diseases. Inactivated vaccines are composed of dead, or inactivated, viruses and bacteria, and therefore differ from live but attenuated vaccines.
The type of vaccine used can differ depending on the infection in question, how the immune system responds to the pathogen the vaccine will treat, and various practical considerations related to the delivery of the vaccine.
How do inactivated vaccines work?
Many vaccines that are regularly used, such as the MMR vaccines and chickenpox vaccines, are live attenuated vaccines. These vaccines have a weakened version of the live virus, to stop it from causing the disease but to still encourage the production of T cells. Inactivated vaccines are another form of vaccine, where the virus is inactivated during the process of making the vaccine.
Inactivated vaccines are not strongly influenced by antibodies in the host body, compared to live vaccines. This means that they can be administered when antibodies are present in the blood, such as during infancy or after being given medication containing antibodies.
Inactivated vaccines cannot replicate and always require repeated doses for immunity to be achieved. The first dose is the one that prepares the immune system to respond, but a protective immune response does not develop until the second or later doses.
Because the virus is dead during the making of the vaccine, they interact with the immune system differently than live, attenuated vaccines. The immune response to live vaccines is similar to encountering the virus itself, whereas inactivated vaccines show little or no cellular immunity. This also means that inactivated vaccines can be used to boost to supplement previous vaccinations.
How are inactivated vaccines made?
To make an inactivated vaccine, the virus has to be grown in culture media. This can often be an initial limiting step in vaccine production, as producers need to understand what conditions encourage viral growth.
Inactivation of the virus is done with heat. Occasionally, inactivation is done with chemicals such as formalin. When the vaccine under production is fractional, meaning it is protein or polysaccharide-based, the vaccine undergoes further purification so that only the subunits of interest remain.
What pathogens can be treated with inactivated vaccines?
Most inactivated vaccines are available as whole-cell inactivated vaccines. These can target viruses such as polio, hepatitis A, and rabies. There are also fractional vaccines for hepatitis B, anthrax, and toxoids such as tetanus.
Several inactivated vaccines have been discontinued. Many diseases have both inactivated and activated vaccine options.
The use of inactivated vaccines, as opposed to live attenuated vaccines, is a contentious issue. For example, inactivated vaccines for influenza are currently available as subunit, rather than whole viral vaccines, in the US. Live, attenuated vaccines can, in rare cases, cause infection of the pathogen and the use of it for influenza has caused hospitalization in some children and elders. This has led to the recommendation of using inactivated vaccines, instead.
However, while inactivated vaccines have been recommended for influenza, they can have reduced efficacy when used in young children. Broader studies comparing live attenuated vaccines with inactivated vaccines have shown that live attenuated vaccines can be 18% more effective in reducing viral attack rate. Furthermore, inactivated vaccines require several infections, which can make them difficult to implement on a broad scale.
Inactivated vaccines against COVID-19
Currently, the vaccine makers of the world are racing to create vaccines against COVID-19. Many of the companies attempting this are resorting to techniques that have been tried and tested, among which are inactivated vaccines.
Sinovac Biotech has created an inactivated whole virus particle vaccine, with an extra immune booster referred to as alum. This has been successful against SARS viruses. The Sinovac vaccine has been approved for use in China with emergency use in some other countries. Various other inactivated COVID-19 vaccines are in development, with three others at various levels of approval.
Inactivated vaccines could be advantageous in the fight against COVID-19 because they can be easily scaled up to large-scale production in many countries. However, the potential effectiveness of inactivated vaccines against COVID-19 is unknown. Current trials with an inactivated vaccine, where inactivation was done with formaldehyde and ultraviolet light, have been effectively used in a mouse model.
References
Belshe, R., Edwards, K., Vesikari, T., Black, S., Walker, R., Hultquist, M., Kemble, G., and Connor, E., 2007. Live Attenuated versus Inactivated Influenza Vaccine in Infants and Young Children. New England Journal of Medicine, 356(7), pp. 685-696.
Cohen, J., 2020. Vaccine designers take first shots at COVID-19. Science, 368(6486), pp. 14-16.
Spruth, M., Kistner, O., Savidis-Dacho, H., Hitter, E., Crowe, B., Gerencer, M., Brühl, P., Grillberger, L., Reiter, M., Tauer, C., Mundt, W. and Barrett, P., 2006. A double-inactivated whole virus candidate SARS coronavirus vaccine stimulates neutralizing and protective antibody responses. Vaccine, 24(5), pp. 652-661.
claim pakar kemudian cakap merapu merabang tak bersandarkan sains punggg semua perlu terima bulat2 , camtu lah pangai pakar2 kat KKM dan sewaktu dgnnyaa
Masaalah nya bioweapon bukan macam conventional weapon yg tembak je mati berlambak boleh di detect tembakan berlaku dan mati serentak terjadi sebaliknya bioweapon sasarannya tak menentu, tak kira usia, timing berbeza, mimik penyakit namun dalam bentuk extreme yg penyakit biasa2 tak berlaku camtu ler .... tapi jumlah yg mati memang abnormal apabila di lihat secara keseluruhan walau tak berlaku serentak sekalipungg
Post time 9-8-2021 11:56 AMFrom the mobile phone|Show all posts
Edited by Dwdrum at 8-8-2021 07:58 PM
Apa antivax boleh buat untuk selamat ummah selain fear mongering?.... Currently hanya ramai akan on side pihak yang proactive untuk selamat kan nyawa....
Gang claimed serba tahu... Pihak america or china mahu depolate manusia.... Yang buat pfizer juga muslim turkey dan ada scientist born as malaysian involved dengan buat vaccine america.. She knows better dari ummah sembang kencang... Layan paranoid....bukti sehingga sekarang haprak..... Aku tidak deny ada case kematiian..... Yang claimed ribu mati di america linked kepada vaccines dari post mortem report tidak sampai 3 digit.... Sembanggggggg... Boleh gang sai baba gang ini....
Post time 9-8-2021 11:59 AMFrom the mobile phone|Show all posts
blastoff replied at 9-8-2021 11:48 AM
Nampak perkataan kau tulis kat bawah ni , bukan stakat BBC dan NYtimes sebut dead /killed virus ta ...
Untuk kesekian kalinya, aku nak bagitahu, inactivated dengan killed, tak sama.
Inactivated tu nyahactive, killed tu dibunuh. Sangat berbeza.
Mana2 journal atau penulisan saintific, tak pernah guna istilah killed virus. Istilah yg digunakan adalah inactivated/weakened/live attenuated virus. Inactivated ni, virus masih berupa seperti asal, cuma dia sudah tidak active, tidak boleh replicate, tidak boleh menjangkiti.
Kalau virus tu dibunuh, tak dipanggil inactivated dah. Bila virus dibunuh, rupa dia pun sudah tidak seperti asal, capsul protein dia terbuka, koyak, genetic material terkeluar.
Virus yg di dalam vaccine, rupa masih seperti asal, intact. Tapi genetic material yg menyumbang kepada sifat2 virus seperti boleh replicate, boleh menjangkiti, telah dinyahaktifkan.
Memang ada website yg tulis killed, sebab penulis pun mungkin tak tahu inactivated dan killed adalah tak sama.
Ko nak teruskan berdebat pasal ni, teruskan. Aku berhenti. Point aku sama sampai bila2. Virus yg dimasukkan adalah inactivated, bukan killed.
Post time 9-8-2021 12:07 PMFrom the mobile phone|Show all posts
blastoff replied at 9-8-2021 11:56 AM
Masaalah nya bioweapon bukan macam conventional weapon yg tembak je mati berlambak boleh di detect ...
Dalam tak sedar memang la manusia yang takde makna bagi mereka ni nak dihapuskan sebanyak boleh tapi yang mereka sangka kan adalah penyelamat mereka.
Sampai 3 kali heart attack, mati hidup balik,mati hidup balik dalam masa beberapa jam sampai macam tu sekali POISON nye tetap lah dianggap sebagai saviour dan ikhtiar, sedangkan yang memberi ikhtiar itu lah pembunuh sebenar mereka hingga apa yang dipesan Nabi Saw dah tak nampak sebagai ikhtiar yang sebenar.
manusia boleh labelkan high tech mak nenek produk yg dia nak promote , talk is cheap, tambah2 penipu lagi laaa akan guna bahasa saintifik itu ini utk nampakkan yg apa yg dia kata atau product yg dia nak promote tuuu veryy high quality.
Tapi yg perlu kita selaku pengguna menilai adalah kesannya ke atas masyarakat kita ler, adakah ada yg teraniaya kerananya ? Dan adakah yg teraniaya itu dapat pembelaan sewajarnya atau simply di perlekehkan disapu bawah karpet di sembunyikan dianggap tak penting etc
Kredibiliti sesuatu pembuat product atau promoter product itu di nilai dari respon yg di tunjukkannya terhadap impak buruk yg TELAH berlaku ler... bukan di nilai dari yg dah ambik tak berlaku apa2 plak ...
Selama nih camtu laa, terhadap semua produk , tetiba je bila mai tang vaksin , yg teraniaya diperlekehkan macam nyawa depa setaraf binatang tak penting tak berharga langsung lah plakkk .... kat situ nampak dah yg pembuat vaksin serta yg dok promote nya tuuuu zeroooo credibility ler
Post time 9-8-2021 12:14 PMFrom the mobile phone|Show all posts
Edited by Inadori at 9-8-2021 12:40 PM
blastoff replied at 9-8-2021 12:03 PM
nampak sgt kau nih jenis "aku betul no matter what"
Walau di beri bukti terang2 kau kantoi pun ...
Aku pun ada bagi bukti, tulisan, video Youtube yg mengatakan virus tu adalah live, weakened, inactivated, so what? Cuma aku tak pandai nak tampal video di sini. Tapi link ada aku bagi, mekanisma Sinovac, guna live, weakened virus.
Aku tak ada kepentingan pun nak tunjukkan aku sahaja yg betul di sini. Aku bercakap sebagai orang sains, aku berdiri teguh dengan fakta aku.
Sebelum ni pun, ada fakta sains ko salah, aku PM ko, tak tegur ko depan2. Kalau aku nak tunjuk aku pandai, lama dah aku tegur ko depan2.
Tapi sekarang, setakat tak setuju yg virus dalam vaccine adalah killed/inactivated/weakened nak terus anggap aku macam musuh, terserah pada ko.
Tengok camna depa perlekehkan apa saja ikhtiar selain dari vaksin punggg dah nampak something wrong dah tuuu.
Walau dok berguguran mati yg dah ambik vaksin dalam jumlah yg alarming pungg, tetap di buat tak nampak lah plak malah diaibkan mangsa dengan menyalahkan setiap usaha "selain vaksin" yg mangsa tu buat sebagai penyebab kematian.
Memang betul2 mata satu style buat judgement ler hanya suci murni kan vaksin sokmo no matter what.... mata satu nih dajal ler so itu teknik brainwash tentera dajal ler yg Nabi sebut muka berlapis2 ( dgn berlayer mask dan faceshield )
Post time 9-8-2021 12:21 PMFrom the mobile phone|Show all posts
blastoff replied at 8-8-2021 01:39 AM
Depa rakam. Boleh ulang tengok kalau x sempat yg live.
https://fb.watch/7egyAHOx5T
Aku tgh tengok
Drpd en. Zolkefli dia bgtau di parlimen adham baba bgtau yg dibg kat rakyat Malaysia adalah experimental vaksin??? Same goes to kJ?!?!
Seriously experimental vaksin?
Kau tengok video nih haaa, senate hearing maaa dah tersembur kluar bukti yg vaksin memang menyebabkan kematian haiwan2 yg di test dgnnya . Tapi macam biasa lah bukti trang tang tang sahih camni pembuat2 vaksin simply upah fact checker utk labelkannya news pelesu ler agar org tak terima bukti nih kekdahnyaa. Sedahsyat tu pembuat2 vaksin melancarkan agenda penipuan .